| Edition |
Fourth edition. |
| Description |
1 online resource (2 volumes (xxv, 1995 pages, 18 unnumbered pages of plates)) : illustrations (chiefly color) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
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text file PDF rda |
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text file html rda |
| Series |
ClinicalKey |
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ClinicalKey.
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| Note |
Previous edition: 2008. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
V: 1 -- The bone organ system: form and function -- The nature of osteoporosis -- Reflections on osteoporosis -- Reflections on development of concepts of intercellular communication in bone -- Osteo-odyssey: a memoir -- Development of the skeleton -- The skeletal stem cell -- Osteoclast biology -- Osteoblast biology -- Osteocyte biology -- The regulatory role of matrix protein in mineralization of bone -- Parathyroid hormone and parathyroid hormone-related protein -- Vitamin D: biology, actions, and clinical implications -- Regulation of bone cell function by estrogens -- Androgens and skeletal biology: basic mechanisms -- Phosphatonins -- Skeletal growth factors -- Wnt signaling in skeletal homeostasis and diseases -- The mechanical behavior of bone -- Cellular and molecular mechanotransduction in bone -- Adaptation of skeletal structure to mechanical loading -- Biomechanics of hip and vertebral fractures -- Prevention of osteoporosis by physical signals: defining a potential role for nondrug strategies in the treatment of musculoskeletal injury and disease -- Epidemiologic methods in studies of osteoporosis -- Genetic determinants of osteoporosis -- Race, ethnicity, and osteoporosis -- Geographic variability in hip and vertebral fractures -- Nutrition and risk for osteoporosis -- Physical activity and exercise in the maintenance of the adult skeleton and the prevention of osteoporotic fractures -- Premenopausal reproductive and hormonal characteristics and the risk for osteoporosis -- Clinical and epidemiological studies: skeletal changes across menopause -- Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization -- Falls as risk factors for fracture -- Nonskeletal risk factors for osteoporosis and fractures -- Outcomes following osteoporotic fractures -- Skeletal heterogeneity and the purposes of bone remodeling: implications for the understanding of osteoporosis -- On the evolution and contemporary roles of bone remodeling -- Cytokines and the pathogenesis of osteoporosis -- Animal models for osteoporosis -- Bone and fat -- Bone mineral acquisition in utero and during infancy and childhood -- Bone acquisition in adolescence. |
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V: 2 -- Osteoporosis in childhood and adolescence -- Osteoporosis associated with pregnancy -- Osteoporosis in premenopausal women -- Estrogen deficiency, postmenopausal osteoporosis, and age-related bone loss -- Immobilization osteoporosis -- Osteoporosis associated with illnesses and medications -- Glucocorticoid-induced osteoporosis -- Anticonvulsant-related bone disease -- Thyroid hormone and the skeleton -- The skeletal actions of parathyroid hormone in primary hyperparathyroidism and in osteoporosis -- Osteogenesis imperfecta and other defects of bone development as occasional causes of adult osteoporosis -- HIV and osteoporosis -- Obesity, diabetes, and fractures -- Osteoporosis in organ transplant patients -- Osteoporosis associated with rheumatologic disorders -- Osteoporosis associated with chronic kidney disease -- Oral bone loss and systemic osteoporosis: weighing the risk benefit ratio of treatment -- Cancer treatment-induced bone loss in patients with breast cancer: pathophysiology and clinical perspectives -- Pathophysiology-prostate cancer -- Mechanisms of bone destruction in myeloma -- Evaluation of the patient at risk for osteoporosis -- Imaging of osteoporosis -- Osteoporosis: who should be treated? Who should be screened? -- Clinical use of bone densitometry -- Biochemical markers of bone turnover in osteoporosis -- Fracture risk assessment: the development and application of FRAX® -- Orthopedic aspects of osteoporosis -- Falls prevention interventions -- Physical therapy, physical modalities, and exercise regimens in the management of osteoporosis -- Calcium in the treatment of osteoporosis -- Vitamin D and its metabolities and analogs in the management of osteoporosis -- Alternative therapy through nutrients and nutraceuticals -- Design considerations for clinical investigations of osteoporosis -- Lessons from bone histomorphometry on the mechanisms of action of osteoporosis drugs -- Estrogen and estrogen analogs for prevention and treatment of osteoporosis -- Androgens -- Calcitonin in osteoporosis -- Bisphosphonates: pharmacology and use in the treatment of osteoporosis -- Osteonecrosis of the jaw and atypical femoral fractures -- Condition critical: compliance and persistence with osteoporosis medications -- Denosumab for the treatment of osteoporosis -- Strontium ranelate in the prevention of osteoporotic fractures -- Parathyroid hormone treatment for osteoporosis -- New approaches to osteoporosis therapeutics -- The past, present, and uncertain future of therapeutic innovation in osteoporosis. |
| Note |
Print version record. |
| Summary |
Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 % continuing to make osteoporosis a hot topic in medicine. |
| Language |
English. |
| Subject |
Osteoporosis.
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Fractures, Bone -- pathology |
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Osteoporosis |
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Osteporosis -- therapy |
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Osteoporosis -- therapy |
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Ostéoporose.
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HEALTH & FITNESS -- Diseases -- Musculoskeletal.
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MEDICAL -- Orthopedics.
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MEDICAL -- Rheumatology.
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Osteoporosis
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| Genre/Form |
Osteoporosis.
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| Added Author |
Marcus, Robert, 1940- editor.
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Feldman, David, 1939- editor.
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Dempster, David W., editor.
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Luckey, Marjorie, editor.
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Cauley, Jane A., editor.
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| Other Form: |
Print version: Osteoporosis. Fourth edition. Amsterdam : Elsevier/Academic Press, 2013 9780124158535 (OCoLC)839312872 |
| ISBN |
9780123982520 (electronic bk.) |
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0123982529 (electronic bk.) |
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1299668232 (ebk) |
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9781299668232 (ebk) |
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9780124158535 |
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0124158536 |
| Standard No. |
Z99954666053 |
|
99954684131 |
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99954666053 |
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AU@ 000051829899 |
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AU@ 000058153148 |
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AU@ 000060905151 |
|
DEBBG BV043957875 |
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DEBBG BV044176246 |
|
DEBSZ 405349416 |
|
DEBSZ 481274022 |
|
DKDLA 820120-katalog:000737932 |
|
NZ1 15349524 |
|
UKMGB 018521369 |
|
