| Description |
1 online resource (xxii, 430 pages) : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Best synthetic methods |
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Best synthetic methods.
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| Summary |
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in this book details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydrates to be thoroughly analysed and assessed, glycobiologists require access to defined target carbohydrates in useful quantities. Thus carbohydrates and glycoconjugates are now recognized as important targets for total synthesis programmes and it is essential to develop efficient regio- and stereoselective methods for the synthesis of carbohydrates. Whilst carbohydrates can sometimes be isolated from natural sources, synthetic strategies often offer the advantage of allowing access to larger quantities of material as well as entry to analogues of the natural carbohydrates. * The latest volume in the long standing Best Synthetic Methods series * Clear chapter by chapter breakdown of carbohydrate synthesis themes with examples of good practical methods for common carbohydrate syntheses. |
| Contents |
An introduction to carbohydrate synthesis (H.M.I. Osborn). Selective hydroxyl protection and deprotection (J. Robertson, P.M. Stafford). Synthesis and activation of carbohydrate donors : acetates, halides, phenylselenides and glycals (B.G. Davis et al.). Synthesis and activation of carbohydrate donors : thioglycosides and sulfoxides (K.P.R. Kartha, R.A. Field). Synthesis and activation of carbohydrate donors : acetimidates, n-pentenyl and vinyl glycosides (A.J. Fairbanks, C.M.P. Seward). Modern glycosidation methods: tuning of reactivity (J. Pietruszka). Modern glycosidation methods: orthogonal glycosidation (J. Pietruszka). The stereoselective synthesis of mannosides (S.C. Ennis, H.M.I. Osborn). Synthesis of sialic acid containing carbohydrates (H. Ando et al.). The synthesis of glycosyl amino acids (P.G. Evans et al.). The synthesis of C-linked glycosides (P. Meo, H.M.I. Osborn). The uses of glycoprocessing enzymes in synthesis (B.G. Davis, S.J. Hancock). |
| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Subject |
Carbohydrates -- Synthesis.
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Glucides -- Synthèse.
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SCIENCE -- Chemistry -- Organic.
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Carbohydrates -- Synthesis
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| Added Author |
Osborn, Helen M. I.
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| Other Form: |
Print version: Carbohydrates. Amsterdam ; London : Academic, 2003 0123120853 9780123120854 (OCoLC)51528744 |
| ISBN |
9780123120854 |
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0123120853 |
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9780080528526 |
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008052852X |
| Standard No. |
AU@ 000056736354 |
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CHDSB 005989000 |
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DEBBG BV039828651 |
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DEBBG BV042313877 |
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DEBSZ 367768895 |
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NZ1 12433216 |
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NZ1 15188863 |
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